3D Print: Stapled Peptides/Estrogen Receptor α

This model has been optimised for 3D printing, it includes structural supports and is approximately 6x4x6cm. PBD: http://www.rcsb.org/structure/2YJA IUPHAR:http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=620 Estrogen receptor alpha is one of two main types of estrogen receptor. This nuclear receptor is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach to small molecules for the modulation of receptor signaling and subsequent gene expression.