Noonan syndrome (NS) is a genetically and phenotypically heterogeneous non-aneuploidic congenital RASopathy. Affected individuals can bear some clinical features similar to that of Turner syndrome.
Cardiopulmonary abnormanlities include:
Pulmonary stenosis (with dysplastic pulmonary valve): the most common cardiac anomaly
hypertrophic cardiomyopathy ,patent ductus arteriosus (PDA)
Model derrived from Post contrast MRA.
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